Satyendra Dhar, MD @DharSaty · 1 month ago
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Prostate-Specific Antigen (PSA) Test • Total PSA (tPSA): o Measures overall PSA levels in the blood. o Used as the primary screening
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Prostate-Specific Antigen (PSA) Test

•	Total PSA (tPSA):
o	Measures overall PSA levels in the blood.
o	Used as the primary screening test.
•	Free PSA (fPSA): 
o	Measures unbound PSA.
o	Lower free PSA percentage suggests a higher cancer risk.
•	PSA Density (PSAD): 
o	Adjusts PSA levels based on prostate volume
o	Helps differentiate BPH from cancer.
•	PSA Velocity (PSAV): 
o	Tracks PSA level changes over time.
o	Rapid increase may indicate aggressive cancer.
•	PSA Doubling Time (PSADT): 
o	Measures how quickly PSA levels double.
o	Faster doubling suggests more aggressive cancer.
•	Pro-PSA & Prostate Health Index (PHI): 
o	Includes p2PSA, total PSA, & free PSA
o	To improve cancer detection & reduce unnecessary biopsies.
•	4Kscore Test: 
o	Evaluates four PSA-related proteins along with clinical factors.
o	To estimate the risk of high-grade cancer.
•	PCA3 Test: 
o	Urine-based genetic test detecting PCA3 mRNA.
o	Highly specific to prostate cancer.
•	IsoPSA Test: 
o	Analyzes PSA structural changes to distinguish benign conditions from cancer.

#PSA #prostatecancer #BPH
Satyendra Dhar, MD @DharSaty · 1 month ago
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