Toxic Alcohol Ingestion: Methanol Solvent found in cleaning and printing solutions, adhesives, stains, paint removers, antifreeze agent in windshield wiping fluid, camp stove fuel, gasoline additive Pharmacology: - Peak serum concentration 30-60 minutes, elimination half-life 12-20 hours - Permanent blindness reported at as little as 0.1 mL/kg (6-10 mL in adults) - Lethal dose = 1-2 mL/kg - Metabolite (eg. formic acid) causes toxicity, but does NOT cause osmolal gap #Diagnosis #Management #Toxicology #Methanol #Ingestion #ALiEM
