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Complications of CKD - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic; water/electrolyte imbalances or endocrine/metabolic derangements are not clinically evident. - These disturbances manifest clinically in CKD stages 4-5 (GFR < 30 mL/min). #Pathophysiology #Nephrology #CKD #Complications