There are 2 Major Types of Angioedema: - Mast cell / histamine mediated – usually presents with angioedema AND allergic symptoms (urticaria, flushing, pruritis, bronchospasm, throat tightness, hypotension) - Bradykinin mediated – presents WITHOUT allergic symptoms, usually history of recurrent swelling; think ACEi #Diagnosis #Angioedema #Classification #Types #Bradykinin