Systemic Inflammatory Response Syndrome (SIRS) Criteria - Definitions of Sepsis, Severe Sepsis and Septic Shock Systemic Inflammatory Response Syndrome (SIRS) Two or more of the following criteria: 1 Heart rate > 90 2 Temp > 100.40F (380C) or < 96.80F (360C) 3 Respiratory rate > 20 or PaC02 < 32 mm Hg 4 WBC > 12,000/mm3 or < 4,000/mm3, or > 1096 band forms Sepsis = SIRS + Suspected or present source of infection Severe Sepsis = Sepsis + Lactic Acidosis or SBP < 90 or SBP drop > 40 (Organ dysfunction, Hypotension, or hypoperfusion) Septic Shock = Severe Sepsis + Hypotension, despite adequate fluid resuscitation #Diagnosis #SIRS #Sepsis #Severe #SepticShock #Definitions #Criteria
