When trying to differentiate between the two conditions think “FAST” with Serotonin Syndrome and “SLOW” with Neuroleptic Malignant Syndrome. Serotonin Syndrome (THINK FAST) - FAST onset - FAST movements (agitation, akathisia, HYPERreflexia) - FAST resolution Neuroleptic Malignant Syndrome (THINK SLOW) - SLOW onset - SLOW movements and HYPOreflexia - SLOW resolution #Diagnosis #Serotonin #Syndrome #NMS #NeurolepticMalignant #Comparison #Table