Aminoglycosides - Antibiotics Class Overview Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV) Spectrum: Extremely efficacious vs. aerobic Gram negatives including Pseudomonas. NO activity vs. Gram positives (except when used for synergy) or anaerobes. Used for: serious gram negative infections especially when Pseudomonas is suspected (pneumonia, bacteremia, urinary tract infections). Used with beta-lactams against gram positive organisms for synergistic effect (mainly in endocarditis). #Pharmacology #Antibiotics #Review #Overview #Aminoglycosides #Gentamicin #Tobramycin #Amikacin #Streptomycin
