Approach to Neonatal Jaundice Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin load (i.e., pre-hepatic; either hemolytic or non-hemolytic processes), (2) impaired bilirubin conjugation (i.e., hepatic) or (3) impaired bilirubin excretion (i.e., post-hepatic). #Diagnosis #Peds #Pediatrics #Neonatal #Jaundice #Algorithm #Differential #Workup #bilirubinemia