Langerhans cell histiocytosis is an uncommon disease characterised by multiple cysts in patients with nicotine abuse. In a very early stage, these patients show only nodules, that later on cavitate and become cysts (figure). As in all smoking related diseases, there is an upper lobe predominance. #Clinical #Radiology #CTChest #LangerhansCellHistiocytosis #LCH #Nodular #RadiologyAssistant