Management of Anaphylaxis in the Outpatient Setting In the management of anaphylaxis, administering intramuscular epinephrine and ensuring proper oxygenation and effective circulation are key. A suggested office-based protocol is shown in Figure 1. Performing a primary survey and providing supportive care for the patient's airway, breathing, and circulation (with administration of epinephrine) are the critical initial steps. Patients should have easy access to commercially made, nonexpired epinephrine autoinjectors, which are preferred for delivering this therapy. #Management #Allergy #Anaphylaxis #Outpatient #Algorithm #Treatment