Acute Coronary Syndrome (ACS) Definitions - Stable Angina, Unstable Angina, NSTEMI, STEMI
1 STABLE ANGINA - Angina pain develops when there is increased demand in the setting of a stable atherosclerotic
plaque. The vessel is unable to dilate enough to allow adequate blood flow to meet the myocardial
2 UNSTABLE ANGINA
- The plaque ruptures and a thrombus forms around the ruptured plaque, causing partial occlusion of the
vessel. Angina pain occurs at rest or progresses rapidly over a short period of time.
3 NSTEMI
- During an NSTEMI, the plaque rupture and thrombus formation causes partial occlusion to the vessel
that results in injury and infarct to the subendocardial myocardium.
4 STEMI
- A STEMI is characterized by complete occlusion the blood vessel lumen, resulting in transmural injury and infarct to the myocardium, which is reflected by ECG changes and a rise in troponins.
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