Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender erythematous plaques or nodules 2. Dense neutrophilic infiltrate on biopsy Minor criteria 1. Fever, temperature >38C 2. Association with an underlying hematologic malignancy, inflammatory disease, or pregnancy or preceded by an upper respiratory or gastrointestinal tract infection 3. Excellent response to treatment with systemic corticosteroids 4. Abnormal laboratory values at presentation (3 of 4): erythrocyte sedimentation rate >20 mm/h; positive C-reactive protein; leukocyte count >10 x 10^3/pL; >70% neutrophils #Sweet #Syndrome #Acute #Febrile #Neutrophilic #Dermatosis #Criteria #Diagnosis #Hematology #Dermatology
