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Markers of Organ Dysfunction in Severe Sepsis Altered consciousness Confusion Psychosis Tachycardia Hypotension Altered CVP Altered PAOP Tachypnoea PaO2 <70mmHg SaO2 < 90% PaO2/FiO2 300% Jaundice Enzymes, PT Albumin Oliguria Anuria Creatinine PT/APTT, D-Dimer Platelets, Protein C #Diagnosis #Organ #Dysfunction #Severe #Sepsis #CriticalCare #Diagnosis #Criteria