Responsiveness-Based Sedation State Definitions 

Minimal sedation (anxiolysis) 
"A drug-induced state during which patients respond normally to verbal commands. Although cognitive 
function and coordination might be impaired, ventilatory and cardiovascular functions are unaffected."

Moderate sedation 
"A drug-induced depression of consciousness during which patients respond purposefully to verbal 
commands, either alone or accompanied by light tactile stimulation. No interventions are required to 
maintain a patent airway, and spontaneous ventilation is adequate. Cardiovascular function is usually 
maintained "
 
Dissociative sedation 
"A trance-like cataleptic state induced by the dissociative drug ketamine characterized by profound 
analgesia and amnesia, with retention of protective airway reflexes, spontaneous respirations, and 
cardiopulmonary stability. "2-6 

Deep sedation 
"A drug-induced depression of consciousness during which patients cannot be easily aroused but respond 
purposefully following repeated or painful stimulation. The ability to independently maintain ventilatory 
function may be impaired. Patients may require assistance in maintaining a patent airway and 
spontaneous ventilation may be inadequate. Cardiovascular function is usually maintained. "34 

General anesthesia 
"A drug-induced loss of consciousness during which patients are not arousable, even by painful 
stimulation. The ability to independently maintain ventilatory function is often impaired. Patients often 
require assistance in maintaining a patent airway, and positive pressure ventilation may be required 
because of depressed spontaneous ventilation or drug-induced depression of neuromuscular function. 
Cardiovascular function may be impaired. " 

#Sedation #Definitions #Procedural #Anesthesia #Minimal #Moderate #General #Deep #Dissociative #Anesthesia #Management
Dr. Aaron Brown @aaronbrown · 6 years ago
GrepMed Anesthesia Editor, UC Davis School of Medicine 2019
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