Lemierre’s Syndrome - Pathophysiology
Lemierre’s is an infectious thrombophlebitis of the internal jugular vein.
- It starts out as a common oropharyngeal infection, such as pharyngitis, tonsillitis, peritonsillar abscess, or dental infection.
- But then if it goes untreated, it can spread to the parapharyngeal space (ie become a deep space neck infection), and get into the carotid sheath.
- Once it penetrates the carotid sheath, it is only a matter of time before the patient becomes bacteremic and a clot forms in the IJ. From there, septic emboli can fly throughout the body, landing in the liver, lungs, endocardium, and joints.
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