Pathogens in Pneumonia

Here is a quick review of the pathogens causing pneumonia (useful for enumerating differentials in your grand rounds/cases)

TYPICAL ORGANISMS (RISK FACTOR): 

- S. pneumoniae (EtOH use. Concomitant flu, IVDU, endobronchial obstruction) 
- H. influenzae (COPD. smoking, concomitant flu. endobronchial obstruction) 
- Moraxella catarrhalis (COPD, smoking) 
- S. aureus (Concomitant Flu, endobronchial obstruction) 
- Grp A strep 
- Gram-negatives (aspiration; Klebsiela & Acinetobacter — EtOH use; Pseudomonas — COPD. smoking. structural lung disease; Burkholderia — structural lung dsease) 

- Anaerobes (EtOH use, aspration, endobronchial obstruction) 

ATYPICAL ORGANISMS (RISK FACTOR): 

- Legionella spp (COPD, smoking. hotel or cruise ships) 
- Mycoplasma pneumoniae 
- Chlamydia pneumoniae (COPD, smoking) 

RESPIRATORY VIRUSES: 

- Influenza 
- Rhinovirus 
- Parainfluenza 
- Adenovirus 
- RSV 
- Human metapneumovirus 
- Coronavirus 
- Human bocavirus 
Others: NTMs. MAC (structural lung disease, smoking) 

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