fractional flow reserve (FFR)
Established measures of coronary physiology.
The fractional flow reserve (FFR) is an index of epicardial
coronary physiology and is measured during maximal
hyperemia. The coronary flow reserve (CR) is a measure
of both the epicardial and microvascular physiology and is
expressed as the ratio of hyperemic to basal flow, simplified to the ratio of basal to hyperemic mean transit time.
The index of microcirculatory resistance (IMR) is a spe-
cific index of the microcirculation and is expressed as the
product of Pd and mean transit time. Pw here indicates the
coronary wedge pressure.
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