Management of patients with known or suspected malignant pleural effusion (MPE) - An Official ATS/STS/STR Clinical Practice Guideline *With goals of assessing lung expansion and relief of dyspnea. This step may not be necessary if the patient’s dyspnea is known to be attributable to the MPE. **Physicians are not great predictors of prognosis. As such, the recommendation of “Predicted very short survival” should be used as a rough guideline and individualized on a case-by-case basis. ***Note: there is a low likelihood (2–4%) of indwelling pleural catheter (IPC)–related infection. Escalation of care (intravenous antibiotics, hospital admission, removal of catheter) should be made on a case-by-case basis and is recommended if there are any signs/symptoms of worsening infection. #Malignant #Pleural #Effusions #MPE #Algorithm #Management #ATS #Guidelines