Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to ADH
 • Pain/Post-op
 • Neurologic trauma
 • Drugs
 • Pulmonary pathology
 • Malignancy
True hypovolemia
 • Bleeding
 • GI losses
 • Renal losses (especially thiazide diuretics)
With edema
 • Congestive heart failure
 • Cirrhosis
 • Nephrotic syndrome
 • Reduced GFR, AKI/CRF
Hormonal changes
 • Hypothyroidism
 • Adrenal insufficiency
 • Pregnancy
Hypo-osmolar urine - Uosm < 100 mmol/kg - ADH suppression
 • Primary polydipsia
 • Insufficient osmole intake

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Dr. Gerald Diaz @GeraldMD · 6 years ago
Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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