Lancisi’s Sign in Severe Tricuspid Regurgitation
A 60-year-old man presented with progressive dyspnea and weight gain. A holosystolic murmur that augmented with inspiration was noted at the left lower sternal border. Examination of the neck revealed a palpable, monomorphic venous pulsation, known as Lancisi’s sign.
Lancisi’s sign is a physical finding of severe tricuspid regurgitation. It is caused by blood flowing backwards into the jugular vein through the incompetent tricuspid valve during ventricular systole.
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