Antibiotics and CNS Diffusion
1. Drugs with good CNS diffusion:
- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole
2. Drugs with moderate CNS diffusion:
- β-lactam agents, Aciclovir, ganciclovir, Vancomycin, Doxycyclin
3. Drugs with low CNS diffusion:
- Daptomycin, Colimycin, Tigecyclin, Aminoglycosides
4. Drugs of no use in CNS infections:
- Echinocandins, Macrolides
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