Diagnostic Criteria for Scleroderma Renal Crisis 1. New onset blood pressure >150/85 mm Hg OR increase 220 mm Hg from usual systolic blood pressure. 2. A decline in renal function, defined as an increase in serum creatinine of >10 % Supportive features: - Microangiopathic hemolytic anemia - Findings consistent with accelerated hypertension on retinal examination - Microscopic hematuria on urine dipstick and/or red blood cells on urine microscopy - Oliguria or anuria - Flash pulmonary edema - Renal biopsy with typical features of SRC including onion skin proliferation within the walls of intrarenal arteries and arterioles, fibrinoid necrosis, glomerular shrinkage #Scleroderma #Renal #Crisis #Diagnosis #Criteria
