Ulcerative Colitis vs Crohn's Disease - IBD Comparison Table Ulcerative Collitis - Location • Always affects rectum extending to varying degrees around the large bowel - Inflammation • Continuous, Diffuse mucosal inflammation (Inflammation limited to the mucosa) • Sharp transition between diseased and normal colon Crohn’s Disease - Location • Anywhere from the mouth to anus • Frequently affects the Terminal ileum • Most cases (70-80%) have small bowel involvement and sparing of the rectum - Inflammation • “Patchy (Skip areas), Transmural Inflammation” • Locality in the setting of relatively normal intervening mucosa, segmental asymmetric involvement of different parts of the wall within given segments of bowel. - Amy Chung, MD, MSc @AmyChung #Ulcerative #Colitis #Crohns #Disease #IBD #Comparison #Table #UC