Von Willebrand Disease - Most common inherited bleeding disorder
Clinical
• Easy bruising
• Skin bleeding
• Prolonged bleeding from mucosal surfaces (oropharyngeal, GI. uterine)
Laboratory
• Normal platelet count (mild thrombocytopenia in type 2B)
• Normal PT/INR
• Normal aPTT (prolonged if very low factor VIII)
Treatment
• Desmopressin (DDAVP)
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