Cerebral Toxoplasmosis - Most comrnon CNS infection in patients with AIDS who are not receiving appropriate prophylaxis Clinical • Headache • Fever • Altered mental status • Seizure Management First line • Sulfadiazine and pyrimethamine • Leucovorin (co-administer to prevent pyrimethamine-induced hematologic toxicity) Second line • Clindamycin plus pyrimethamine plus leucovorin • Atovaquone plus pyrimethamine plus leucovorin #Cerebral #Toxoplasmosis #Diagnosis #Overview #Management
