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Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities, but has this distinction has HUGE treatment implications : TTP has high rates of morbidity and mortality, and first-line treatment is plasma exchange. When in doubt, start plasma exchange while awaiting confirmatory testing for TTP #Thrombotic #Microangiopathy #thrombocytopenic #purpura #TTP #HemolyticUremicSyndrome #HUS #thrombocytopenia #Comparison #Diagnosis #Table #Hematology