Mechanical Ventilation: The Basics
In the most basic sense, ventilator modes are defined by their control variable and settings.
Breaths are triggered (started) and cycled (ended) by specific parameters, which are determined by the mode.
While there are many modes to choose from, we will review the most basic below.
Assist Control / Volume Control (AC/VC):
• Delivers mandatory breaths at a fixed rate with a set volume (control) and allows spontaneous breaths to be triggered, but will assist those breaths with the full set volume as well (assist).
• Volume Cycled, Delivers volume until set volume goal is reached
• Volume: 6-8 cc/kg IBW, RR: depends on pt/scenario, PEEP: ARDSnet PEEP ladder, FiO2: goal spO2 > 88%
Assist Control / Pressure Control (AC/PC):
• Delivers mandatory breaths at a fixed rate with a set pressure for a set inspiratory time (control) and allows spontaneous breaths to be triggered, but will assist those breaths with the full set pressure and i-time as well (assist).
• Time Cycled, Delivers set pressure for set inspiratory time (i-time)
• PC: adjust to achieve Vte, RR: depends on pt/scenario, PEEP: ARDSnet PEEP ladder, FiO2: goal spO2 > 88%
Pressure Support Ventilation (PSV):
• Often, a "weaning" mode. Unlike in AC modes, in PSV all breaths are spontaneous with pressure to support the breath, but not "control" it (no mandated volume or i-time).
• Flow Cycled, Delivers pressure support until flow has reached 25% of its peak
• PS: 0-8, if in an SBT, RR: spontaneous, PEEP: 5-8, FiO2: goal spO2 > 88%
Dr. Meredith Greer @EmmGeezee
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Extracorporeal Membrane Oxygenation (ECMO) - Basics
Mode of cardiopulmonary support used to treat pulmonary and/or cardiovascular failure with an external artificial circuit
ECMO GOALS:
• Maintain adequate tissue oxygenation to allow recovery from potentially reversible cardiopulmonary failure
• Adjust ventilator settings with very low tidal volumes, allowing for lung rest, minimizing further ventilator-induced lung injury
• ECMO is a bridge, not a destination
Veno-Arterial (VA)
• Supports heart and lungs (complete cardiopulmonary support)
• Blood drains - venous system
• Blood returns - arterial system
Veno-Venous (VV)
• Suppots lungs (pulmonary support only)
• Blood drains - venous system
• Blood returns - venous system
E-CPR
• Rapid deployment of VA-ECMO when CPR is unsuccessful in achieving sustained return of spontaneous circulation
PARAMETERS
Flow (mL/kg/min):
• Dial in RPMs and flow depends on resistance in patient & circuit
• Generally set between 4-6 Lmin (100-150 mL/kg/min in children)
• On VA-ECMO - flow supports cardiac output
• On VV-ECMO - flow supports oxygenation
Sweep (L/min): Sweep gas flow determines PCO2 clearance (ie, ventilation) for both VV- & VA-ECMO
OXYGEN DELIVERY
• From both lungs & oxygenator
• Assess perfusion (eg, NIRS, SVO2, lactate)
REST SETTINGS
• If ventilated, frequently placed on low "rest" settings with moderate PEEP
• Bronchoscopy may be needed for plugging
ANTICOAGULATION
• To reduce risk of thromboembolism in circuit
• Done per institutional protocol
ELECTROLYTE REPLACEMENT
• Particularly Ca+ due to citrate binding
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