Pneumocystis jirovecii Pneumonia Clinical • Caused by Pneumocystis jirovecii (formerly carinil) • Immunocompromised host (HIV, transplant) • Seen in HIV positive patients with CD4 < 200 • Symptoms progress over 2—3 weeks • Fever, dry cough • Oxygen desaturation common with ambulation • LDH is often elevated Treatment • Steroids for Pa02 < 70 or A-a gradient > 35 • Trimethoprim-sulfamethoxazole (TMP-SMX) #Pneumocystis #jirovecii #PJP #Pneumonia #Diagnosis #Management
