Histamine Fish Toxicity - Inadequate refrigeration increases enzyme from bacteria on fish Clinical • Skin flushing, throbbing headache, abdominal cramps • Oral burning, nausea, diarrhea, palpitations • Symptoms occur within 10-30 min of eating fish Management • Supportive care • Antihistamines (e.g. diphenhydramine) #Histamine #Fish #Toxicity #Toxicology #Diagnosis