Torsades de Pointes
• "Twisting of the pointes"
• QRS axis swings from positive to negative direction single lead
• Originates from single focus
• Usually precipitated by drugs that prolong the QT interval
Class IA antidysrhythmics (procainamide, quridine)
Class IC antidysrhythmics (propafenone, necanide)
Cyclc antidepressants
Droperidol
Phenothiazines
Azithromycin
Methadone
• Also precipitated by electrolyte abnormaüties
Hypomagnesemia
Hypokalemia
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