Staphylococcal Scalded Skin Syndrome (SSSS) (aka Ritter disease) Nikolsky positive Clinical • Typically occurs 3 to 7 days of age • Rare at birth • Fever, irritable • Erythroderma (often begins around mouth) • Blisters appear in areas of mechanical stress (flexural areas, buttocks, hands, feet) • Conjunctivitis Management • Supportive • Nafcillin or oxacillin (or any anti-staphylococcal) • Vancomycin (if high prevalence of CA-MRSA or initial treatment failure) #Staphylococcal #Scalded #Skin #Syndrome #SSSS Staphylococcus #Ritters #Diagnosis
