Metformin - First Line Treatment for Diabetes Type 2 • Start with initial dose of 500 mg daily • Adjust dose Increase dose gradually to 2000 mg daily if tolerated • Consider extended-release form to minimize risk of gastrointestinal (GI) adverse effects • Try extended-release form and consider using highest dose tolerable rather than stopping medication #Metformin #Indications #Titration #Pharmacology #Diabetes #DM2 #Prescribing
