Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS 
 - Nephrotoxins (NSAlDs, contrast, OTCs, herbals, abx, illicits, chemo, immunosuppression) 
 - Hx of AKI/CKD 
 - Recent hypo/hypertension? 
 - TTE/liver fxn? 
 - BMP, cap, CBC w/ diff 
 - Urinalysis/microscopy/UOP/weights 
 - Urine Na/K/Cl/urea/protein/Cr 
 - Renal/bladder US w/ PVR 
 - CPK, uric acid (rhabdo/TLS) 

Causes of Inpatient AKI (Liano 1996) 
 - ATN - 45%
 - Pre-renal disease — 21% 
 - AKI on CKD— 13% (mostly ATN and pre-renal) 
 - Urinary tract obstruction — 10% (most often prostate related) 
 - Glomerulonephritis or vasculitis — 4% 
 - Atheroemboli — 1% 

#AcuteKidneyInjury #AKI #Nephrology #Diagnosis #Algorithm #Causes #Differential
NephSim (www.nephsim.com) @Neph_Sim · 5 years ago
nephsim.com is a free educational tool that uses interactive cases, media, and infographics to teach nephrology topics including glomerular diseases, acid/base disorders, kidney transplant, electrolyte abnormalities, dialysis, & more! https://twitter.com/Neph_Sim
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