Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS - Nephrotoxins (NSAlDs, contrast, OTCs, herbals, abx, illicits, chemo, immunosuppression) - Hx of AKI/CKD - Recent hypo/hypertension? - TTE/liver fxn? - BMP, cap, CBC w/ diff - Urinalysis/microscopy/UOP/weights - Urine Na/K/Cl/urea/protein/Cr - Renal/bladder US w/ PVR - CPK, uric acid (rhabdo/TLS) Causes of Inpatient AKI (Liano 1996) - ATN - 45% - Pre-renal disease — 21% - AKI on CKD— 13% (mostly ATN and pre-renal) - Urinary tract obstruction — 10% (most often prostate related) - Glomerulonephritis or vasculitis — 4% - Atheroemboli — 1% #AcuteKidneyInjury #AKI #Nephrology #Diagnosis #Algorithm #Causes #Differential