Guide to Acute Kidney Injury (AKI)
What to ask/look for:
- HPI, PMH, full ROS
- Nephrotoxins (NSAlDs, contrast, OTCs, herbals, abx, illicits, chemo, immunosuppression)
- Hx of AKI/CKD
- Recent hypo/hypertension?
- TTE/liver fxn?
- BMP, cap, CBC w/ diff
- Urinalysis/microscopy/UOP/weights
- Urine Na/K/Cl/urea/protein/Cr
- Renal/bladder US w/ PVR
- CPK, uric acid (rhabdo/TLS)
Causes of Inpatient AKI (Liano 1996)
- ATN - 45%
- Pre-renal disease — 21%
- AKI on CKD— 13% (mostly ATN and pre-renal)
- Urinary tract obstruction — 10% (most often prostate related)
- Glomerulonephritis or vasculitis — 4%
- Atheroemboli — 1%
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