Proposed Schema for the Management of Pruritus in Primary Biliary Cholangitis (PBC).
Cholestyramine up to 4g x 4day
Rifampicin 150 mg/day
Increase up to 60 mg/day every other week
Naltrexone up to 50 mg/day
Sertraline up to 100 mg/day
Extracorporeal albumin dialysis
Plasmapheresis
Consider transplantation
d, day; h, hours; EOW, every other week; MARS, Molecular Adsorbent Recirculating System; CBD, common bile duct
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