Proposed Schema for the Management of Pruritus in Primary Biliary Cholangitis (PBC). Cholestyramine up to 4g x 4day Rifampicin 150 mg/day Increase up to 60 mg/day every other week Naltrexone up to 50 mg/day Sertraline up to 100 mg/day Extracorporeal albumin dialysis Plasmapheresis Consider transplantation d, day; h, hours; EOW, every other week; MARS, Molecular Adsorbent Recirculating System; CBD, common bile duct #Pruritus #Primary #Biliary #Cholangitis #PBC #Management #Hepatology #Algorithm