On the left a patient with GGO as dominant pattern. In addition there is traction bronchiectasis indicating the presence of fibrosis. This case is one of the possible patterns of nonspecific interstitial pneumonia (NSIP). NSIP is characterized histologically by a relatively uniform pattern of cellular interstitial inflammation associated with variable degrees of fibrosis. As in UIP (usual interstitial pneumonia) it mainly involves the dependent regions of the lower lobes, but NSIP lacks the extensive fibrosis with honeycombing. NSIP may be idiopathic or associated with collagen vascular diseases or exposure to drugs or chemicals. NSIP has a relative good prognosis and the majority of patients respond to treatment with corticosteroids. This outcome is quite different from that seen in UIP, which has a poor prognosis. #Clinical #Radiology #CTChest #NSIP #NonspecificInterstitialPneumonia #GroundGlass #GGO #RadiologyAssistant
