The differential diagnosis for an elevated MCHC (mean corpuscular hemoglobin concentration) includes: Conditions with Abnormal RBCs: • Abnormal RBC • Spherocytosis • Sickle cells • Hemoglobin C • Xerocytosis • RBC agglutination Situations where plasma opacification leads to a falsely elevated Hgb: • Hyperlipidemia • Hemolysis (i.e., free hemoglobin) - Dr. Tony Breu @tony_breu #Elevated #MCHC #Differential #Diagnosis #Laboratory
