Sequential Approach to the Uremic Patient with Pruritus Optimize dialysis adequacy Use biocompatible membranes for HD Optimize nutrition Patient education - Break scratch-itch cycle: - apply cold cloths or - exert pressure on itching region Emollients Antihistamines Capsaicin 0.025% cream; ultraviolet B therapy; oral activated charcoal'; long-chain essential tatty acids* Gabapentin 100-300 mg orally after dialysis Nalfurafine 5 mg orally per day Thalidomide 100 mg daily—patients beyond reproductive age (max. 3 months) Consider serotonin antagonists, naltroxono, tacro imus ointment, kototifen Sequential Approach to the Patient with Pruritus #Uremic #Uremia #Pruritis #Management #Sequential #Algorithm #Nephrology