Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP (Hemolysis, Elevated Liver tests, Low Platelets) * Variant of pre-eclampsia * High LDH, schistocytes, DIC * Responds to delivery of child * Severe cases may require plasma exchange 2) Fatty liver of pregnancy * Severe coagulation defects and liver failure * Responds to delivery of child 3) TTP * Occurs most often in 2nd trimester * Can support mother through pregnancy with plasma exchange - Dr. Tom DeLoughery @Bloodman #Thrombocytopenia #Pregnancy #TTPHUS #HELLP #AFLP #Obstetrics #OBGyn #Hematology #Diagnosis #Comparison #Table
