Bisphosphonates for Osteoporosis Treatment or Prevention Bisphosphonates are common medications used in the treatment and prevention of osteoporosis. There are 4 drugs in this class with approved osteoporosis indications. There are a variety of dosing frequencies, from daily, weekly, monthly, to yearly. Bisphosophonates inhibit osteoclasts, which in turn increase bone mineral density. Important counseling points is to take the oral versions with water but on an empty stomach, ensure to keep an empty stomach for at least 30 minutes after and remain upright for that entire time. Ibandronate is the same points except 60 minutes instead of 30 min. Jarred Prudencio, PharmD - https://www.instagram.com/ambcarerx #Bisphosphonates #Dosing #Schedule #Frequency #Pharmacology #Endocrinology #Osteoporosis #Management