Atopic Dermatitis - Topical Treatment Options
First Line: Topical Corticosteroids
- High Potency: Betamethasone dipropionate, clobetasol, halobetasol
- Medium Potency: Triamcinolone, Fluticasone
- Low Potency: Desonide, Hydrocortisone
Topical Calcineurin Inhibitors
- Elidel (pimecrolimus)
- Protopic (tacrolimus)
Phosphodiesterase-4 (PDE4) Inhibitor
- Eucrisa (crisaborol)
Atopic dermatitis is the most common form of eczema. It is a chronic condition in which patients can have times of remission and times of flare-ups. The first line therapy is non-pharmacologic, but many patients require at least the first line pharmacologic option which is topical corticosteroids (TCS). Remember that we have different strengths/potencies of the topical corticosteroids, and that long-term use of the higher potency products is not recommended. If patients using TCS products do not have good enough responses, we can use topical calcineurin inhibitors or the topical PDE4 inhibitor. If all topical products do not work and patient has moderate/severe atopic dermatitis, we can consider the use of the biologic agent Dupixent.
Jarred Prudencio, PharmD - https://www.instagram.com/ambcarerx
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