Approach to chronic meningitis (defined as lasting for 4 weeks or more, and separate from recurrent acute meningitis) based on immune status of the patient, clinical presentation, and neuroimaging findings. – Bacterial: spirochetes (syphilis, Lyme), listeria, with more possibilities depending on immune status – Viral: HIV, enterovirus – Fungal: cryptococcus, coccidioides, blastomyces, histoplasma, sporothrix – Mycobacterial: tuberculosis and non-TB mycobacteria – Parasitic: strongyloides, cysticercosis, toxoplasma – Neoplastic: solid (melanoma, adenocarcinoma) and liquid (ALL, CNS lymphoma) – Inflammatory: Sarcoidosis, Behcet’s #chronic #meningitis #Differential #Diagnosis
