Erythema Nodosum - Causes and Differential Diagnosis Appearance: erythematous painful lumps usually 1-6 cm in diameter Almost ALWAYS on anterior shins but can spread to thighs RARELY ulcerate or necrose USUALLY resolve spontaneously within 2-8 weeks (can sometimes have “bruising” around the areas during healing process) #Erythema #Nodosum #Causes #Differential Diagnosis #Dermatology #SkinRash #Clinical