Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs) What are the side effects? - Immune-related adverse events (IRAEs) of check point inhibitors are unfortunately common, and can effect any organ (see picture below from NEJM review article- a great overview on the topic!) When do IRAEs occur? - IRAEs usually develop within the first few weeks to months after treatment initiation, but can occur at any time How are IRAEs treated? - Most immune-related adverse events are effectively treated by stopping the checkpoint inhibitor and inducing temporary immunosuppression with steroids or other immunosuppresion #CheckPointInhibitors #SideEffects #IRAEs #AdverseEffects #Oncology
