Capillary filling time is measured by applying firm pressure on the ventral surface of the distal phalanx of the right index finger with a glass microscope object holder. 

- The pressure is increased until the skin is blank and then held for 10 seconds.
- The return time of normal skin color is recorded with a stopwatch. 
- A fill time of more than 3 seconds is defined as abnormal.

This is the technique that was used in the ANDROMEDA-SHOCK study

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