Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease Increased Thrombosis Increased Platelet-Vesset Wall Interaction • Incr von Willebrand factor • Incr ADAMTS 13 High Thrombin Generation • Incr Factor VIII • Decr Protein C, Protein S • Decr Antithrombin • Decr TFPI Low Fibrinolysis • Decr Plasminogen • Incr PAI #Thrombosis #Bleeding #Clot #Cirrhosis #Pathophysiology #Hepatology #Liver
