Phases of Colchicine Toxicity - Early Phase (0-24h) - Multi-organ failure Phase (1-7 days) - Recovery Phase (7-21 days) Respiratory: Respiratory Distress Syndrome Cardiovascular: Congestive heart failure, Cardiac arrhythmia, cardiac arrest Neurologic: Seizures, Encephalopathy, Cerebral edema, myopathy Hematologic: Cytopenias, Bone marrow suppression, Hemolysis, DIC Metabolic: Metabolic acidosis, HypoK, hypoNa, hypoP04, hypoglycemia/hyperglycemia Other: Renal failure, Liver failure, Immune compromise & Sepsis By Dr. Kathryn Watson @Kat_Watson #Colchicine #Toxicity #Toxicology #Phases #Pharmacology #Diagnosis
