Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin, Ketoconazole Decreased Aldosterone Release: ACE inhibitors, ARBs Decreased Renin Release: NSAIDs, Beta-Blockers Decreased Na, K-ATPase and Aldosterone Receptor Function: Cyclosporine, Tacrolimus - Amelia Furbish PharmD Student @ https://www.instagram.com/happypill #Hyperkalemia #Pathophysiology #Pharmacology #Impaired #Potassium #Renal