Malignant Pericardial Effusion on POCUS Echocardiogram Which of the following is the most common etiology for this finding in the United States? Resolution: Malignancy (particularly lung, breast, melanoma, leukemia, lymphoma), followed closely by uremia, is the most common cause of pericardial effusion in the United States among those listed. Tuberculosis is the most common cause of pericardial effusion world wide. #Malignant #Pericardial #Effusion #POCUS #Echocardiogram #Cardiology #clinical #ultrasound