Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined significance (MGUS) A bone marrow can be deferred in patients with small (<1.5 gm/dL) IgM MGUS, low-risk MGUS (IgG type, M- protein <1.5 gm/dL, normal free light-chain ratio), and small (involved/uninvolved serum-free light-chain ratio <8) light-chain MGUS in whom there are no clinical features concerning for myeloma or lymphoplasmacytic malignancy. #monoclonal #gammopathy #MGUS #Biopsy #algorithm #diagnosis #management #hematology #multiplemyeloma
