Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus (Decr ADH production or release) - Idiopathic - Neurosurgery - Trauma - Infiltrative disorders (e.g. sarcoidosis, histiocytosisX, granulomatosiswith polyangiitis) - Malignancy - CNS infections - Various rare genetic/congenital disorders Nephrogenic Diabetes Insipidus (Incr ADH sensitivity in kidneys) - Medications (e.g. lithium, amphotericin, demeclocycline, ifosfamide, cisplatin) - Chronic hypercalcemia - Chronic hypokalemia - Various renal diseases (e.g. renal amyloidosis, multiple myeloma Sjogren’ssyndrome, sickle cell disease) - Various rare genetic disorders - Pregnancy Dr. Eric Strong https://twitter.com/DrEricStrong #Hypernatremia #Differential #Diagnosis #Table #Causes
